The Vibram Five Kinger show (called VFF by many) is a unique foot glove that allows you to run in a barefoot style while being protected from road hazards. The VFF Bikila is designed especially for road running. Here is a video introduction to the shoe and my first impressions.
For those interested in more information regarding these shoes here are some links:
Main Product Link: http://www.vibramfivefingers.com/products/Five-Fingers-BikilaLS-Mens.htm
Best fan site on Vibram Bikila I have found: http://birthdayshoes.com/bikila